Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | all-ab-ratio-log-sorted |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | REACTOME_TRANSLATION |
| Enrichment Score (ES) | -0.39830887 |
| Normalized Enrichment Score (NES) | -1.8126192 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.007909306 |
| FWER p-Value | 0.185 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RPN1 | RPN1 Entrez, Source | ribophorin I | 262 | 1.276 | -0.0680 | No |
| 2 | RPS27A | RPS27A Entrez, Source | ribosomal protein S27a | 323 | 1.157 | -0.0712 | No |
| 3 | UBA52 | UBA52 Entrez, Source | ubiquitin A-52 residue ribosomal protein fusion product 1 | 324 | 1.157 | -0.0548 | No |
| 4 | EIF3G | 364 | 1.094 | -0.0520 | No | ||
| 5 | RPS15 | RPS15 Entrez, Source | ribosomal protein S15 | 446 | 0.977 | -0.0647 | No |
| 6 | EIF3B | 455 | 0.968 | -0.0536 | No | ||
| 7 | SRP9 | SRP9 Entrez, Source | signal recognition particle 9kDa | 516 | 0.898 | -0.0606 | No |
| 8 | SEC61B | SEC61B Entrez, Source | Sec61 beta subunit | 595 | 0.801 | -0.0748 | No |
| 9 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 665 | 0.735 | -0.0870 | No |
| 10 | RPS28 | RPS28 Entrez, Source | ribosomal protein S28 | 687 | 0.717 | -0.0837 | No |
| 11 | EIF3I | 709 | 0.698 | -0.0807 | No | ||
| 12 | RPS27 | RPS27 Entrez, Source | ribosomal protein S27 (metallopanstimulin 1) | 792 | 0.630 | -0.0987 | No |
| 13 | TRAM1 | TRAM1 Entrez, Source | translocation associated membrane protein 1 | 912 | 0.523 | -0.1304 | No |
| 14 | EIF4A1 | EIF4A1 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 1 | 1016 | 0.458 | -0.1577 | No |
| 15 | EIF4A2 | EIF4A2 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 2 | 1041 | 0.440 | -0.1594 | No |
| 16 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 1064 | 0.423 | -0.1606 | No |
| 17 | EIF3A | 1105 | 0.384 | -0.1683 | No | ||
| 18 | SEC61G | SEC61G Entrez, Source | Sec61 gamma subunit | 1144 | 0.358 | -0.1757 | No |
| 19 | SPCS3 | SPCS3 Entrez, Source | signal peptidase complex subunit 3 homolog (S. cerevisiae) | 1240 | 0.297 | -0.2027 | No |
| 20 | EIF3H | 1248 | 0.292 | -0.2008 | No | ||
| 21 | GSPT2 | GSPT2 Entrez, Source | G1 to S phase transition 2 | 1274 | 0.271 | -0.2052 | No |
| 22 | SRPR | SRPR Entrez, Source | signal recognition particle receptor ('docking protein') | 1291 | 0.259 | -0.2067 | No |
| 23 | EIF2B1 | EIF2B1 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa | 1333 | 0.233 | -0.2169 | No |
| 24 | RPL12 | RPL12 Entrez, Source | ribosomal protein L12 | 1337 | 0.232 | -0.2146 | No |
| 25 | RPL7A | RPL7A Entrez, Source | ribosomal protein L7a | 1360 | 0.217 | -0.2187 | No |
| 26 | EEF1D | EEF1D Entrez, Source | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 1364 | 0.214 | -0.2167 | No |
| 27 | ETF1 | ETF1 Entrez, Source | eukaryotic translation termination factor 1 | 1366 | 0.213 | -0.2140 | No |
| 28 | EIF3C | 1380 | 0.202 | -0.2154 | No | ||
| 29 | RPL15 | RPL15 Entrez, Source | ribosomal protein L15 | 1392 | 0.196 | -0.2162 | No |
| 30 | EEF1B2 | EEF1B2 Entrez, Source | eukaryotic translation elongation factor 1 beta 2 | 1395 | 0.193 | -0.2141 | No |
| 31 | EIF3K | 1398 | 0.189 | -0.2121 | No | ||
| 32 | EEF1A1 | EEF1A1 Entrez, Source | eukaryotic translation elongation factor 1 alpha 1 | 1411 | 0.175 | -0.2135 | No |
| 33 | EIF2B5 | EIF2B5 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa | 1423 | 0.171 | -0.2147 | No |
| 34 | SRPRB | SRPRB Entrez, Source | signal recognition particle receptor, B subunit | 1431 | 0.165 | -0.2147 | No |
| 35 | EEF2 | EEF2 Entrez, Source | eukaryotic translation elongation factor 2 | 1432 | 0.165 | -0.2123 | No |
| 36 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 1434 | 0.164 | -0.2103 | No |
| 37 | RPL32 | RPL32 Entrez, Source | ribosomal protein L32 | 1442 | 0.156 | -0.2104 | No |
| 38 | RPL28 | RPL28 Entrez, Source | ribosomal protein L28 | 1455 | 0.150 | -0.2122 | No |
| 39 | EIF2S2 | EIF2S2 Entrez, Source | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 1477 | 0.140 | -0.2171 | No |
| 40 | SRP14 | SRP14 Entrez, Source | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 1504 | 0.120 | -0.2240 | No |
| 41 | RPS2 | RPS2 Entrez, Source | ribosomal protein S2 | 1554 | 0.085 | -0.2389 | No |
| 42 | EIF1AX | EIF1AX Entrez, Source | eukaryotic translation initiation factor 1A, X-linked | 1632 | 0.045 | -0.2635 | No |
| 43 | EIF3E | 1646 | 0.037 | -0.2673 | No | ||
| 44 | SEC11A | 1715 | -0.002 | -0.2896 | No | ||
| 45 | RPL29 | RPL29 Entrez, Source | ribosomal protein L29 | 1783 | -0.039 | -0.3111 | No |
| 46 | RPL27A | RPL27A Entrez, Source | ribosomal protein L27a | 1824 | -0.066 | -0.3233 | No |
| 47 | EIF3F | 1835 | -0.072 | -0.3255 | No | ||
| 48 | RPS13 | RPS13 Entrez, Source | ribosomal protein S13 | 1836 | -0.072 | -0.3245 | No |
| 49 | RPL21 | RPL21 Entrez, Source | ribosomal protein L21 | 1842 | -0.075 | -0.3251 | No |
| 50 | SSR4 | SSR4 Entrez, Source | signal sequence receptor, delta (translocon-associated protein delta) | 1850 | -0.080 | -0.3262 | No |
| 51 | FAU | FAU Entrez, Source | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived); ribosomal protein S30 | 1873 | -0.101 | -0.3320 | No |
| 52 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 1902 | -0.116 | -0.3396 | No |
| 53 | RPS29 | RPS29 Entrez, Source | ribosomal protein S29 | 1916 | -0.123 | -0.3421 | No |
| 54 | RPL10A | RPL10A Entrez, Source | ribosomal protein L10a | 1941 | -0.141 | -0.3480 | No |
| 55 | RPL11 | RPL11 Entrez, Source | ribosomal protein L11 | 1984 | -0.171 | -0.3593 | No |
| 56 | EIF3D | 2032 | -0.197 | -0.3720 | No | ||
| 57 | RPS5 | RPS5 Entrez, Source | ribosomal protein S5 | 2048 | -0.206 | -0.3740 | No |
| 58 | RPS14 | RPS14 Entrez, Source | ribosomal protein S14 | 2056 | -0.216 | -0.3732 | No |
| 59 | RPS8 | RPS8 Entrez, Source | ribosomal protein S8 | 2062 | -0.220 | -0.3718 | No |
| 60 | RPL39 | RPL39 Entrez, Source | ribosomal protein L39 | 2137 | -0.260 | -0.3924 | No |
| 61 | RPL4 | RPL4 Entrez, Source | ribosomal protein L4 | 2143 | -0.262 | -0.3903 | No |
| 62 | RPL6 | RPL6 Entrez, Source | ribosomal protein L6 | 2152 | -0.269 | -0.3891 | No |
| 63 | RPS20 | RPS20 Entrez, Source | ribosomal protein S20 | 2181 | -0.288 | -0.3942 | Yes |
| 64 | RPS9 | RPS9 Entrez, Source | ribosomal protein S9 | 2188 | -0.294 | -0.3920 | Yes |
| 65 | RPS16 | RPS16 Entrez, Source | ribosomal protein S16 | 2194 | -0.297 | -0.3894 | Yes |
| 66 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 2199 | -0.302 | -0.3865 | Yes |
| 67 | SSR3 | SSR3 Entrez, Source | signal sequence receptor, gamma (translocon-associated protein gamma) | 2217 | -0.317 | -0.3875 | Yes |
| 68 | SPCS2 | SPCS2 Entrez, Source | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 2221 | -0.319 | -0.3840 | Yes |
| 69 | RPS6 | RPS6 Entrez, Source | ribosomal protein S6 | 2223 | -0.320 | -0.3798 | Yes |
| 70 | RPS7 | RPS7 Entrez, Source | ribosomal protein S7 | 2225 | -0.326 | -0.3754 | Yes |
| 71 | RPS3A | RPS3A Entrez, Source | ribosomal protein S3A | 2245 | -0.343 | -0.3768 | Yes |
| 72 | EIF5B | EIF5B Entrez, Source | eukaryotic translation initiation factor 5B | 2263 | -0.362 | -0.3772 | Yes |
| 73 | EIF4H | 2276 | -0.368 | -0.3760 | Yes | ||
| 74 | RPL18 | RPL18 Entrez, Source | ribosomal protein L18 | 2291 | -0.376 | -0.3752 | Yes |
| 75 | RPL27 | RPL27 Entrez, Source | ribosomal protein L27 | 2315 | -0.403 | -0.3770 | Yes |
| 76 | RPS3 | RPS3 Entrez, Source | ribosomal protein S3 | 2324 | -0.410 | -0.3738 | Yes |
| 77 | RPS18 | RPS18 Entrez, Source | ribosomal protein S18 | 2327 | -0.414 | -0.3686 | Yes |
| 78 | RPS21 | RPS21 Entrez, Source | ribosomal protein S21 | 2331 | -0.416 | -0.3637 | Yes |
| 79 | RPL13A | RPL13A Entrez, Source | ribosomal protein L13a | 2350 | -0.432 | -0.3635 | Yes |
| 80 | RPS25 | RPS25 Entrez, Source | ribosomal protein S25 | 2379 | -0.451 | -0.3663 | Yes |
| 81 | EIF2B3 | EIF2B3 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa | 2386 | -0.457 | -0.3617 | Yes |
| 82 | RPN2 | RPN2 Entrez, Source | ribophorin II | 2393 | -0.465 | -0.3571 | Yes |
| 83 | EIF2S1 | EIF2S1 Entrez, Source | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | 2401 | -0.474 | -0.3526 | Yes |
| 84 | SSR1 | SSR1 Entrez, Source | signal sequence receptor, alpha (translocon-associated protein alpha) | 2403 | -0.475 | -0.3462 | Yes |
| 85 | RPL8 | RPL8 Entrez, Source | ribosomal protein L8 | 2406 | -0.477 | -0.3401 | Yes |
| 86 | RPS24 | RPS24 Entrez, Source | ribosomal protein S24 | 2468 | -0.526 | -0.3527 | Yes |
| 87 | RPL13 | RPL13 Entrez, Source | ribosomal protein L13 | 2477 | -0.536 | -0.3477 | Yes |
| 88 | RPS26 | RPS26 Entrez, Source | ribosomal protein S26 | 2508 | -0.564 | -0.3495 | Yes |
| 89 | RPS15A | RPS15A Entrez, Source | ribosomal protein S15a | 2529 | -0.588 | -0.3477 | Yes |
| 90 | RPL18A | RPL18A Entrez, Source | ribosomal protein L18a | 2544 | -0.601 | -0.3438 | Yes |
| 91 | RPS12 | RPS12 Entrez, Source | ribosomal protein S12 | 2545 | -0.602 | -0.3352 | Yes |
| 92 | RPL24 | RPL24 Entrez, Source | ribosomal protein L24 | 2568 | -0.627 | -0.3335 | Yes |
| 93 | RPL17 | RPL17 Entrez, Source | ribosomal protein L17 | 2581 | -0.638 | -0.3284 | Yes |
| 94 | EIF5 | EIF5 Entrez, Source | eukaryotic translation initiation factor 5 | 2586 | -0.643 | -0.3206 | Yes |
| 95 | RPL5 | RPL5 Entrez, Source | ribosomal protein L5 | 2587 | -0.643 | -0.3114 | Yes |
| 96 | RPL14 | RPL14 Entrez, Source | ribosomal protein L14 | 2593 | -0.647 | -0.3038 | Yes |
| 97 | RPS4X | RPS4X Entrez, Source | ribosomal protein S4, X-linked | 2610 | -0.670 | -0.2996 | Yes |
| 98 | RPL23A | RPL23A Entrez, Source | ribosomal protein L23a | 2618 | -0.683 | -0.2922 | Yes |
| 99 | RPL37A | RPL37A Entrez, Source | ribosomal protein L37a | 2640 | -0.711 | -0.2890 | Yes |
| 100 | RPL7 | RPL7 Entrez, Source | ribosomal protein L7 | 2649 | -0.722 | -0.2813 | Yes |
| 101 | RPSA | RPSA Entrez, Source | ribosomal protein SA | 2659 | -0.732 | -0.2739 | Yes |
| 102 | RPL19 | RPL19 Entrez, Source | ribosomal protein L19 | 2665 | -0.735 | -0.2651 | Yes |
| 103 | RPL34 | RPL34 Entrez, Source | ribosomal protein L34 | 2667 | -0.739 | -0.2549 | Yes |
| 104 | RPL30 | RPL30 Entrez, Source | ribosomal protein L30 | 2669 | -0.742 | -0.2447 | Yes |
| 105 | EEF1G | EEF1G Entrez, Source | eukaryotic translation elongation factor 1 gamma | 2671 | -0.743 | -0.2344 | Yes |
| 106 | RPL10 | RPL10 Entrez, Source | ribosomal protein L10 | 2701 | -0.776 | -0.2329 | Yes |
| 107 | RPL31 | RPL31 Entrez, Source | ribosomal protein L31 | 2718 | -0.794 | -0.2269 | Yes |
| 108 | RPLP2 | RPLP2 Entrez, Source | ribosomal protein, large, P2 | 2727 | -0.803 | -0.2181 | Yes |
| 109 | RPL35 | RPL35 Entrez, Source | ribosomal protein L35 | 2733 | -0.811 | -0.2082 | Yes |
| 110 | RPL3 | RPL3 Entrez, Source | ribosomal protein L3 | 2740 | -0.822 | -0.1985 | Yes |
| 111 | RPL36 | RPL36 Entrez, Source | ribosomal protein L36 | 2752 | -0.838 | -0.1902 | Yes |
| 112 | EIF3J | 2753 | -0.839 | -0.1783 | Yes | ||
| 113 | RPS10 | RPS10 Entrez, Source | ribosomal protein S10 | 2762 | -0.859 | -0.1687 | Yes |
| 114 | RPL35A | RPL35A Entrez, Source | ribosomal protein L35a | 2783 | -0.885 | -0.1627 | Yes |
| 115 | RPS11 | RPS11 Entrez, Source | ribosomal protein S11 | 2803 | -0.914 | -0.1559 | Yes |
| 116 | RPL38 | RPL38 Entrez, Source | ribosomal protein L38 | 2804 | -0.916 | -0.1429 | Yes |
| 117 | RPLP1 | RPLP1 Entrez, Source | ribosomal protein, large, P1 | 2806 | -0.919 | -0.1302 | Yes |
| 118 | SRP54 | SRP54 Entrez, Source | signal recognition particle 54kDa | 2818 | -0.935 | -0.1205 | Yes |
| 119 | DDOST | DDOST Entrez, Source | dolichyl-diphosphooligosaccharide-protein glycosyltransferase | 2822 | -0.942 | -0.1081 | Yes |
| 120 | RPL9 | RPL9 Entrez, Source | ribosomal protein L9 | 2848 | -0.979 | -0.1024 | Yes |
| 121 | EIF2B2 | EIF2B2 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa | 2857 | -0.990 | -0.0909 | Yes |
| 122 | RPS23 | RPS23 Entrez, Source | ribosomal protein S23 | 2894 | -1.046 | -0.0879 | Yes |
| 123 | SRP68 | SRP68 Entrez, Source | signal recognition particle 68kDa | 2917 | -1.094 | -0.0796 | Yes |
| 124 | EIF2S3 | EIF2S3 Entrez, Source | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 2984 | -1.225 | -0.0838 | Yes |
| 125 | SRP72 | SRP72 Entrez, Source | signal recognition particle 72kDa | 2988 | -1.242 | -0.0672 | Yes |
| 126 | RPL22 | RPL22 Entrez, Source | ribosomal protein L22 | 3020 | -1.357 | -0.0581 | Yes |
| 127 | RPS17 | RPS17 Entrez, Source | ribosomal protein S17 | 3048 | -1.454 | -0.0462 | Yes |
| 128 | SRP19 | SRP19 Entrez, Source | signal recognition particle 19kDa | 3127 | -1.902 | -0.0448 | Yes |
| 129 | EIF2B4 | EIF2B4 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa | 3138 | -2.015 | -0.0195 | Yes |
| 130 | RPL23 | RPL23 Entrez, Source | ribosomal protein L23 | 3149 | -2.132 | 0.0076 | Yes |
