Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | all-ab-ratio-log-sorted |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | REACTOME_TRANSCRIPTION |
| Enrichment Score (ES) | -0.6048702 |
| Normalized Enrichment Score (NES) | -2.45953 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TCEB1 | TCEB1 Entrez, Source | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 175 | 1.535 | -0.0272 | No |
| 2 | POLR2E | POLR2E Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide E, 25kDa | 186 | 1.500 | -0.0021 | No |
| 3 | RNMT | RNMT Entrez, Source | RNA (guanine-7-) methyltransferase | 278 | 1.242 | -0.0078 | No |
| 4 | POLR2C | POLR2C Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide C, 33kDa | 365 | 1.093 | -0.0148 | No |
| 5 | POLR2H | POLR2H Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide H | 371 | 1.083 | 0.0041 | No |
| 6 | SNRPD3 | SNRPD3 Entrez, Source | small nuclear ribonucleoprotein D3 polypeptide 18kDa | 445 | 0.978 | -0.0009 | No |
| 7 | TAF9 | TAF9 Entrez, Source | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa | 728 | 0.683 | -0.0785 | No |
| 8 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 826 | 0.600 | -0.0983 | No |
| 9 | TCEB2 | TCEB2 Entrez, Source | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) | 961 | 0.492 | -0.1320 | No |
| 10 | GTF2F2 | GTF2F2 Entrez, Source | general transcription factor IIF, polypeptide 2, 30kDa | 1006 | 0.464 | -0.1373 | No |
| 11 | GTF2E2 | GTF2E2 Entrez, Source | general transcription factor IIE, polypeptide 2, beta 34kDa | 1546 | 0.088 | -0.3086 | No |
| 12 | RBM8A | RBM8A Entrez, Source | RNA binding motif protein 8A | 1569 | 0.078 | -0.3142 | No |
| 13 | SNRPB | SNRPB Entrez, Source | small nuclear ribonucleoprotein polypeptides B and B1 | 1579 | 0.071 | -0.3158 | No |
| 14 | SSB | SSB Entrez, Source | Sjogren syndrome antigen B (autoantigen La) | 1655 | 0.032 | -0.3393 | No |
| 15 | POLR1C | POLR1C Entrez, Source | polymerase (RNA) I polypeptide C, 30kDa | 1683 | 0.015 | -0.3476 | No |
| 16 | GTF2F1 | GTF2F1 Entrez, Source | general transcription factor IIF, polypeptide 1, 74kDa | 1692 | 0.013 | -0.3500 | No |
| 17 | GTF2B | GTF2B Entrez, Source | general transcription factor IIB | 1696 | 0.010 | -0.3507 | No |
| 18 | SNRPG | SNRPG Entrez, Source | small nuclear ribonucleoprotein polypeptide G | 1913 | -0.121 | -0.4178 | No |
| 19 | POLR2B | POLR2B Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 1998 | -0.178 | -0.4414 | No |
| 20 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 2065 | -0.221 | -0.4584 | No |
| 21 | TFAM | TFAM Entrez, Source | transcription factor A, mitochondrial | 2102 | -0.243 | -0.4653 | No |
| 22 | SNRPF | SNRPF Entrez, Source | small nuclear ribonucleoprotein polypeptide F | 2186 | -0.292 | -0.4865 | No |
| 23 | CDK7 | CDK7 Entrez, Source | cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) | 2214 | -0.314 | -0.4892 | No |
| 24 | CSTF2 | CSTF2 Entrez, Source | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa | 2242 | -0.343 | -0.4914 | No |
| 25 | SUPT5H | SUPT5H Entrez, Source | suppressor of Ty 5 homolog (S. cerevisiae) | 2266 | -0.363 | -0.4919 | No |
| 26 | MAGOH | MAGOH Entrez, Source | mago-nashi homolog, proliferation-associated (Drosophila) | 2273 | -0.366 | -0.4869 | No |
| 27 | SSRP1 | SSRP1 Entrez, Source | structure specific recognition protein 1 | 2356 | -0.434 | -0.5051 | No |
| 28 | NUDT21 | NUDT21 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 2421 | -0.493 | -0.5163 | No |
| 29 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 2429 | -0.496 | -0.5092 | No |
| 30 | CBX3 | CBX3 Entrez, Source | chromobox homolog 3 (HP1 gamma homolog, Drosophila) | 2691 | -0.760 | -0.5786 | No |
| 31 | SRSF3 | 2759 | -0.851 | -0.5840 | No | ||
| 32 | GTF2E1 | GTF2E1 Entrez, Source | general transcription factor IIE, polypeptide 1, alpha 56kDa | 2825 | -0.944 | -0.5870 | Yes |
| 33 | UPF3B | UPF3B Entrez, Source | UPF3 regulator of nonsense transcripts homolog B (yeast) | 2880 | -1.032 | -0.5849 | Yes |
| 34 | U2AF1 | U2AF1 Entrez, Source | U2 small nuclear RNA auxiliary factor 1 | 2897 | -1.057 | -0.5701 | Yes |
| 35 | SRSF5 | 2952 | -1.151 | -0.5657 | Yes | ||
| 36 | HIST1H2AB | HIST1H2AB Entrez, Source | histone cluster 1, H2ab | 2964 | -1.185 | -0.5468 | Yes |
| 37 | HIST1H2AC | HIST1H2AC Entrez, Source | histone cluster 1, H2ac | 2965 | -1.185 | -0.5245 | Yes |
| 38 | HIST1H2AD | HIST1H2AD Entrez, Source | histone cluster 1, H2ad | 2966 | -1.185 | -0.5021 | Yes |
| 39 | HIST1H2AJ | HIST1H2AJ Entrez, Source | histone cluster 1, H2aj | 2969 | -1.185 | -0.4804 | Yes |
| 40 | HIST2H2AA3 | HIST2H2AA3 Entrez, Source | histone cluster 2, H2aa3 | 2970 | -1.185 | -0.4580 | Yes |
| 41 | HIST2H2AC | HIST2H2AC Entrez, Source | histone cluster 2, H2ac | 2971 | -1.185 | -0.4356 | Yes |
| 42 | HIST1H2BC | HIST1H2BC Entrez, Source | histone cluster 1, H2bc | 2995 | -1.263 | -0.4191 | Yes |
| 43 | HIST1H2BD | HIST1H2BD Entrez, Source | histone cluster 1, H2bd | 2996 | -1.263 | -0.3953 | Yes |
| 44 | HIST1H2BH | HIST1H2BH Entrez, Source | histone cluster 1, H2bh | 2997 | -1.263 | -0.3714 | Yes |
| 45 | HIST1H2BK | HIST1H2BK Entrez, Source | histone cluster 1, H2bk | 2998 | -1.263 | -0.3476 | Yes |
| 46 | HIST1H2BL | HIST1H2BL Entrez, Source | histone cluster 1, H2bl | 2999 | -1.263 | -0.3237 | Yes |
| 47 | HIST1H2BM | HIST1H2BM Entrez, Source | histone cluster 1, H2bm | 3000 | -1.263 | -0.2999 | Yes |
| 48 | HIST1H2BN | HIST1H2BN Entrez, Source | histone cluster 1, H2bn | 3001 | -1.263 | -0.2760 | Yes |
| 49 | SRSF6 | 3012 | -1.321 | -0.2543 | Yes | ||
| 50 | POLRMT | POLRMT Entrez, Source | polymerase (RNA) mitochondrial (DNA directed) | 3052 | -1.463 | -0.2392 | Yes |
| 51 | TCEA1 | TCEA1 Entrez, Source | transcription elongation factor A (SII), 1 | 3071 | -1.544 | -0.2158 | Yes |
| 52 | SRSF7 | 3113 | -1.769 | -0.1955 | Yes | ||
| 53 | SRSF1 | 3116 | -1.796 | -0.1622 | Yes | ||
| 54 | SRSF2 | 3120 | -1.838 | -0.1285 | Yes | ||
| 55 | SRSF11 | 3134 | -1.949 | -0.0958 | Yes | ||
| 56 | HIST1H4A | HIST1H4A Entrez, Source | histone cluster 1, H4a | 3143 | -2.055 | -0.0596 | Yes |
| 57 | SRRM1 | SRRM1 Entrez, Source | serine/arginine repetitive matrix 1 | 3171 | -3.632 | 0.0003 | Yes |
