Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | all-ab-ratio-log-sorted |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | REACTOME_TELOMERE_MAINTENANCE |
| Enrichment Score (ES) | -0.5817126 |
| Normalized Enrichment Score (NES) | -1.9866478 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0018445282 |
| FWER p-Value | 0.035 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PRIM2 | 128 | 1.741 | 0.0215 | No | ||
| 2 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 240 | 1.326 | 0.0337 | No |
| 3 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 430 | 1.005 | 0.0095 | No |
| 4 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 448 | 0.974 | 0.0389 | No |
| 5 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 511 | 0.903 | 0.0515 | No |
| 6 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 608 | 0.784 | 0.0490 | No |
| 7 | RFC4 | RFC4 Entrez, Source | replication factor C (activator 1) 4, 37kDa | 631 | 0.765 | 0.0693 | No |
| 8 | POLD2 | POLD2 Entrez, Source | polymerase (DNA directed), delta 2, regulatory subunit 50kDa | 742 | 0.670 | 0.0583 | No |
| 9 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 1223 | 0.307 | -0.0834 | No |
| 10 | RPA1 | RPA1 Entrez, Source | replication protein A1, 70kDa | 1299 | 0.253 | -0.0982 | No |
| 11 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 1309 | 0.247 | -0.0923 | No |
| 12 | POLA1 | POLA1 Entrez, Source | polymerase (DNA directed), alpha 1 | 1726 | -0.009 | -0.2243 | No |
| 13 | RUVBL2 | RUVBL2 Entrez, Source | RuvB-like 2 (E. coli) | 2035 | -0.197 | -0.3152 | No |
| 14 | RPA3 | RPA3 Entrez, Source | replication protein A3, 14kDa | 2295 | -0.378 | -0.3840 | No |
| 15 | RUVBL1 | RUVBL1 Entrez, Source | RuvB-like 1 (E. coli) | 2318 | -0.405 | -0.3766 | No |
| 16 | HIST1H2AB | HIST1H2AB Entrez, Source | histone cluster 1, H2ab | 2964 | -1.185 | -0.5394 | Yes |
| 17 | HIST1H2AC | HIST1H2AC Entrez, Source | histone cluster 1, H2ac | 2965 | -1.185 | -0.4970 | Yes |
| 18 | HIST1H2AD | HIST1H2AD Entrez, Source | histone cluster 1, H2ad | 2966 | -1.185 | -0.4547 | Yes |
| 19 | HIST1H2AJ | HIST1H2AJ Entrez, Source | histone cluster 1, H2aj | 2969 | -1.185 | -0.4129 | Yes |
| 20 | HIST2H2AA3 | HIST2H2AA3 Entrez, Source | histone cluster 2, H2aa3 | 2970 | -1.185 | -0.3706 | Yes |
| 21 | HIST2H2AC | HIST2H2AC Entrez, Source | histone cluster 2, H2ac | 2971 | -1.185 | -0.3282 | Yes |
| 22 | HIST1H2BC | HIST1H2BC Entrez, Source | histone cluster 1, H2bc | 2995 | -1.263 | -0.2904 | Yes |
| 23 | HIST1H2BD | HIST1H2BD Entrez, Source | histone cluster 1, H2bd | 2996 | -1.263 | -0.2452 | Yes |
| 24 | HIST1H2BH | HIST1H2BH Entrez, Source | histone cluster 1, H2bh | 2997 | -1.263 | -0.2000 | Yes |
| 25 | HIST1H2BK | HIST1H2BK Entrez, Source | histone cluster 1, H2bk | 2998 | -1.263 | -0.1549 | Yes |
| 26 | HIST1H2BL | HIST1H2BL Entrez, Source | histone cluster 1, H2bl | 2999 | -1.263 | -0.1097 | Yes |
| 27 | HIST1H2BM | HIST1H2BM Entrez, Source | histone cluster 1, H2bm | 3000 | -1.263 | -0.0646 | Yes |
| 28 | HIST1H2BN | HIST1H2BN Entrez, Source | histone cluster 1, H2bn | 3001 | -1.263 | -0.0194 | Yes |
| 29 | HIST1H4A | HIST1H4A Entrez, Source | histone cluster 1, H4a | 3143 | -2.055 | 0.0092 | Yes |
