Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | all-ab-ratio-log-sorted |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS |
| Enrichment Score (ES) | 0.49678817 |
| Normalized Enrichment Score (NES) | 1.8307077 |
| Nominal p-value | 0.0014144272 |
| FDR q-value | 0.009593628 |
| FWER p-Value | 0.13 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 184 | 1.508 | -0.0130 | Yes |
| 2 | DIS3 | 192 | 1.488 | 0.0304 | Yes | ||
| 3 | PRKCD | PRKCD Entrez, Source | protein kinase C, delta | 270 | 1.256 | 0.0441 | Yes |
| 4 | PSMD6 | PSMD6 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 277 | 1.243 | 0.0803 | Yes |
| 5 | PSMD8 | PSMD8 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 311 | 1.176 | 0.1058 | Yes |
| 6 | RPS27A | RPS27A Entrez, Source | ribosomal protein S27a | 323 | 1.157 | 0.1377 | Yes |
| 7 | UBA52 | UBA52 Entrez, Source | ubiquitin A-52 residue ribosomal protein fusion product 1 | 324 | 1.157 | 0.1732 | Yes |
| 8 | EXOSC2 | EXOSC2 Entrez, Source | exosome component 2 | 335 | 1.148 | 0.2052 | Yes |
| 9 | HNRNPD | 494 | 0.918 | 0.1825 | Yes | ||
| 10 | PSMC3 | PSMC3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 499 | 0.910 | 0.2091 | Yes |
| 11 | PSME1 | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 566 | 0.848 | 0.2139 | Yes |
| 12 | PSME2 | PSME2 Entrez, Source | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 570 | 0.840 | 0.2387 | Yes |
| 13 | HSPA1B | HSPA1B Entrez, Source | heat shock 70kDa protein 1B | 624 | 0.769 | 0.2452 | Yes |
| 14 | PSME4 | PSME4 Entrez, Source | proteasome (prosome, macropain) activator subunit 4 | 648 | 0.749 | 0.2608 | Yes |
| 15 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 665 | 0.735 | 0.2781 | Yes |
| 16 | PSMB9 | PSMB9 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 684 | 0.719 | 0.2944 | Yes |
| 17 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 724 | 0.685 | 0.3028 | Yes |
| 18 | EXOSC6 | EXOSC6 Entrez, Source | exosome component 6 | 727 | 0.684 | 0.3232 | Yes |
| 19 | PSMD5 | PSMD5 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | 749 | 0.665 | 0.3368 | Yes |
| 20 | PSMC2 | PSMC2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 770 | 0.649 | 0.3503 | Yes |
| 21 | EXOSC4 | EXOSC4 Entrez, Source | exosome component 4 | 791 | 0.630 | 0.3632 | Yes |
| 22 | PSMB7 | PSMB7 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 7 | 797 | 0.622 | 0.3806 | Yes |
| 23 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 798 | 0.622 | 0.3997 | Yes |
| 24 | ANP32A | ANP32A Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 816 | 0.608 | 0.4129 | Yes |
| 25 | PSMD9 | PSMD9 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 | 852 | 0.577 | 0.4193 | Yes |
| 26 | PSMD14 | PSMD14 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 861 | 0.564 | 0.4340 | Yes |
| 27 | PSMB1 | PSMB1 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 1 | 871 | 0.557 | 0.4482 | Yes |
| 28 | HSPB1 | HSPB1 Entrez, Source | heat shock 27kDa protein 1 | 910 | 0.524 | 0.4521 | Yes |
| 29 | AKT1 | AKT1 Entrez, Source | v-akt murine thymoma viral oncogene homolog 1 | 921 | 0.517 | 0.4647 | Yes |
| 30 | PSMA2 | PSMA2 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 2 | 940 | 0.504 | 0.4744 | Yes |
| 31 | PSMB10 | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 960 | 0.493 | 0.4834 | Yes |
| 32 | PSMC1 | PSMC1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 966 | 0.490 | 0.4968 | Yes |
| 33 | PSMB8 | PSMB8 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 1081 | 0.406 | 0.4725 | No |
| 34 | PSMC5 | PSMC5 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | 1124 | 0.371 | 0.4704 | No |
| 35 | PSMD3 | PSMD3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 1262 | 0.281 | 0.4349 | No |
| 36 | PSMC6 | PSMC6 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 1298 | 0.254 | 0.4314 | No |
| 37 | EXOSC5 | EXOSC5 Entrez, Source | exosome component 5 | 1311 | 0.245 | 0.4351 | No |
| 38 | YWHAZ | YWHAZ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 1329 | 0.236 | 0.4368 | No |
| 39 | PSMB2 | PSMB2 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 2 | 1343 | 0.227 | 0.4396 | No |
| 40 | EXOSC3 | EXOSC3 Entrez, Source | exosome component 3 | 1347 | 0.224 | 0.4455 | No |
| 41 | PSMD7 | PSMD7 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog) | 1362 | 0.215 | 0.4476 | No |
| 42 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 1434 | 0.164 | 0.4298 | No |
| 43 | PSMA4 | PSMA4 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 4 | 1441 | 0.159 | 0.4327 | No |
| 44 | TNPO1 | TNPO1 Entrez, Source | transportin 1 | 1447 | 0.155 | 0.4358 | No |
| 45 | PSMA1 | PSMA1 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 1 | 1476 | 0.140 | 0.4311 | No |
| 46 | PSMB3 | PSMB3 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 3 | 1481 | 0.134 | 0.4340 | No |
| 47 | PSMD12 | PSMD12 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 1490 | 0.128 | 0.4353 | No |
| 48 | YWHAB | YWHAB Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 1503 | 0.121 | 0.4352 | No |
| 49 | ELAVL1 | ELAVL1 Entrez, Source | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) | 1531 | 0.099 | 0.4295 | No |
| 50 | PSMA3 | PSMA3 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 3 | 1562 | 0.081 | 0.4223 | No |
| 51 | PSMD11 | PSMD11 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 1585 | 0.069 | 0.4174 | No |
| 52 | PSMA6 | PSMA6 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 6 | 1600 | 0.057 | 0.4146 | No |
| 53 | PSMD13 | PSMD13 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 1641 | 0.041 | 0.4030 | No |
| 54 | PSMA7 | PSMA7 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 7 | 1675 | 0.020 | 0.3929 | No |
| 55 | PSMB4 | PSMB4 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 4 | 1713 | -0.002 | 0.3811 | No |
| 56 | PSMC4 | PSMC4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 1732 | -0.011 | 0.3756 | No |
| 57 | PSMF1 | PSMF1 Entrez, Source | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 1755 | -0.023 | 0.3693 | No |
| 58 | EXOSC1 | EXOSC1 Entrez, Source | exosome component 1 | 1781 | -0.039 | 0.3624 | No |
| 59 | PSMB6 | PSMB6 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 6 | 1868 | -0.099 | 0.3378 | No |
| 60 | PSMA5 | PSMA5 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 5 | 1900 | -0.115 | 0.3313 | No |
| 61 | PSMD1 | PSMD1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 1957 | -0.151 | 0.3179 | No |
| 62 | PSMD10 | PSMD10 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 2041 | -0.202 | 0.2974 | No |
| 63 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 2203 | -0.303 | 0.2549 | No |
| 64 | PSMD4 | PSMD4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 2230 | -0.329 | 0.2566 | No |
| 65 | PSMB5 | PSMB5 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 5 | 2284 | -0.372 | 0.2510 | No |
| 66 | HSPA8 | HSPA8 Entrez, Source | heat shock 70kDa protein 8 | 2935 | -1.126 | 0.0763 | No |
