Datasetall-ab-ratio-log-sorted
PhenotypeNoPhenotypeAvailable
Upregulated in classna_pos
GeneSetREACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE
Enrichment Score (ES)0.5284273
Normalized Enrichment Score (NES)1.8609303
Nominal p-value0.0
FDR q-value0.00752897
FWER p-Value0.089
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CDK1991.9060.0441Yes
2UBE2E1UBE2E1
Entrez,  Source
ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)1521.5970.0909Yes
3UBE2CUBE2C
Entrez,  Source
ubiquitin-conjugating enzyme E2C2191.3980.1253Yes
4PSMD6PSMD6
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 62771.2430.1564Yes
5PSMD8PSMD8
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 83111.1760.1926Yes
6RPS27ARPS27A
Entrez,  Source
ribosomal protein S27a3231.1570.2351Yes
7UBA52UBA52
Entrez,  Source
ubiquitin A-52 residue ribosomal protein fusion product 13241.1570.2811Yes
8SKP14840.9350.2674Yes
9PSMC3PSMC3
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 34990.9100.2990Yes
10PSME1PSME1
Entrez,  Source
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)5660.8480.3116Yes
11PSME2PSME2
Entrez,  Source
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)5700.8400.3440Yes
12PSME4PSME4
Entrez,  Source
proteasome (prosome, macropain) activator subunit 46480.7490.3492Yes
13PSMB9PSMB9
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)6840.7190.3665Yes
14PSMD5PSMD5
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 57490.6650.3724Yes
15PSMC2PSMC2
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 27700.6490.3918Yes
16PSMB7PSMB7
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 77970.6220.4082Yes
17PSMD2PSMD2
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 27980.6220.4329Yes
18PSMD9PSMD9
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 98520.5770.4389Yes
19PSMD14PSMD14
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 148610.5640.4588Yes
20PSMB1PSMB1
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 18710.5570.4780Yes
21CUL1CUL1
Entrez,  Source
cullin 19270.5150.4809Yes
22PSMA2PSMA2
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 29400.5040.4971Yes
23PSMB10PSMB10
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 109600.4930.5106Yes
24PSMC1PSMC1
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 19660.4900.5284Yes
25PSMB8PSMB8
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)10810.4060.5081No
26PSMC5PSMC5
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 511240.3710.5093No
27PSMD3PSMD3
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 312620.2810.4766No
28PSMC6PSMC6
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 612980.2540.4755No
29PSMB2PSMB2
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 213430.2270.4704No
30PSMD7PSMD7
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog)13620.2150.4732No
31PSMA4PSMA4
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 414410.1590.4545No
32PSMA1PSMA1
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 114760.1400.4492No
33PSMB3PSMB3
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 314810.1340.4533No
34PSMD12PSMD12
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1214900.1280.4558No
35PSMA3PSMA3
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 315620.0810.4363No
36PSMD11PSMD11
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1115850.0690.4320No
37PSMA6PSMA6
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 616000.0570.4297No
38PSMD13PSMD13
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1316410.0410.4185No
39CDK2CDK2
Entrez,  Source
cyclin-dependent kinase 216590.0290.4143No
40PSMA7PSMA7
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 716750.0200.4102No
41PSMB4PSMB4
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 41713-0.0020.3985No
42PSMC4PSMC4
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 41732-0.0110.3931No
43PSMF1PSMF1
Entrez,  Source
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)1755-0.0230.3870No
44PSMB6PSMB6
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 61868-0.0990.3551No
45PSMA5PSMA5
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 51900-0.1150.3498No
46PSMD1PSMD1
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11957-0.1510.3378No
47PSMD10PSMD10
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 102041-0.2020.3193No
48PSMD4PSMD4
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 42230-0.3290.2721No
49CDC16CDC16
Entrez,  Source
CDC16 cell division cycle 16 homolog (S. cerevisiae)2254-0.3540.2788No
50PSMB5PSMB5
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 52284-0.3720.2843No
Table: GSEA details [plain text format]



Fig 2: REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE: Random ES distribution   
Gene set null distribution of ES for REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE