Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | all-ab-ratio-log-sorted |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX |
| Enrichment Score (ES) | -0.44887552 |
| Normalized Enrichment Score (NES) | -1.9478058 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0024153974 |
| FWER p-Value | 0.051 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RPS27A | RPS27A Entrez, Source | ribosomal protein S27a | 323 | 1.157 | -0.0802 | No |
| 2 | UBA52 | UBA52 Entrez, Source | ubiquitin A-52 residue ribosomal protein fusion product 1 | 324 | 1.157 | -0.0557 | No |
| 3 | PPP2CA | PPP2CA Entrez, Source | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | 372 | 1.081 | -0.0481 | No |
| 4 | RPS15 | RPS15 Entrez, Source | ribosomal protein S15 | 446 | 0.977 | -0.0511 | No |
| 5 | PPP2R1A | PPP2R1A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform | 521 | 0.891 | -0.0563 | No |
| 6 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 665 | 0.735 | -0.0871 | No |
| 7 | RPS28 | RPS28 Entrez, Source | ribosomal protein S28 | 687 | 0.717 | -0.0787 | No |
| 8 | RPS27 | RPS27 Entrez, Source | ribosomal protein S27 (metallopanstimulin 1) | 792 | 0.630 | -0.0991 | No |
| 9 | EIF4A3 | 1256 | 0.286 | -0.2430 | No | ||
| 10 | GSPT2 | GSPT2 Entrez, Source | G1 to S phase transition 2 | 1274 | 0.271 | -0.2428 | No |
| 11 | RPL12 | RPL12 Entrez, Source | ribosomal protein L12 | 1337 | 0.232 | -0.2580 | No |
| 12 | RPL7A | RPL7A Entrez, Source | ribosomal protein L7a | 1360 | 0.217 | -0.2605 | No |
| 13 | ETF1 | ETF1 Entrez, Source | eukaryotic translation termination factor 1 | 1366 | 0.213 | -0.2577 | No |
| 14 | RPL15 | RPL15 Entrez, Source | ribosomal protein L15 | 1392 | 0.196 | -0.2616 | No |
| 15 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 1434 | 0.164 | -0.2714 | No |
| 16 | RPL32 | RPL32 Entrez, Source | ribosomal protein L32 | 1442 | 0.156 | -0.2704 | No |
| 17 | RPL28 | RPL28 Entrez, Source | ribosomal protein L28 | 1455 | 0.150 | -0.2711 | No |
| 18 | RPS2 | RPS2 Entrez, Source | ribosomal protein S2 | 1554 | 0.085 | -0.3011 | No |
| 19 | RBM8A | RBM8A Entrez, Source | RNA binding motif protein 8A | 1569 | 0.078 | -0.3040 | No |
| 20 | RPL29 | RPL29 Entrez, Source | ribosomal protein L29 | 1783 | -0.039 | -0.3722 | No |
| 21 | RPL27A | RPL27A Entrez, Source | ribosomal protein L27a | 1824 | -0.066 | -0.3837 | No |
| 22 | RPS13 | RPS13 Entrez, Source | ribosomal protein S13 | 1836 | -0.072 | -0.3858 | No |
| 23 | RPL21 | RPL21 Entrez, Source | ribosomal protein L21 | 1842 | -0.075 | -0.3858 | No |
| 24 | FAU | FAU Entrez, Source | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived); ribosomal protein S30 | 1873 | -0.101 | -0.3934 | No |
| 25 | RPS29 | RPS29 Entrez, Source | ribosomal protein S29 | 1916 | -0.123 | -0.4044 | No |
| 26 | RPL10A | RPL10A Entrez, Source | ribosomal protein L10a | 1941 | -0.141 | -0.4092 | No |
| 27 | RPL11 | RPL11 Entrez, Source | ribosomal protein L11 | 1984 | -0.171 | -0.4192 | No |
| 28 | RPS5 | RPS5 Entrez, Source | ribosomal protein S5 | 2048 | -0.206 | -0.4352 | No |
| 29 | RPS14 | RPS14 Entrez, Source | ribosomal protein S14 | 2056 | -0.216 | -0.4329 | No |
| 30 | RPS8 | RPS8 Entrez, Source | ribosomal protein S8 | 2062 | -0.220 | -0.4299 | No |
| 31 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 2065 | -0.221 | -0.4259 | No |
| 32 | RPL39 | RPL39 Entrez, Source | ribosomal protein L39 | 2137 | -0.260 | -0.4434 | Yes |
| 33 | RPL4 | RPL4 Entrez, Source | ribosomal protein L4 | 2143 | -0.262 | -0.4395 | Yes |
| 34 | RPL6 | RPL6 Entrez, Source | ribosomal protein L6 | 2152 | -0.269 | -0.4364 | Yes |
| 35 | RPS20 | RPS20 Entrez, Source | ribosomal protein S20 | 2181 | -0.288 | -0.4394 | Yes |
| 36 | RPS9 | RPS9 Entrez, Source | ribosomal protein S9 | 2188 | -0.294 | -0.4351 | Yes |
| 37 | RPS16 | RPS16 Entrez, Source | ribosomal protein S16 | 2194 | -0.297 | -0.4305 | Yes |
| 38 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 2199 | -0.302 | -0.4254 | Yes |
| 39 | RPS6 | RPS6 Entrez, Source | ribosomal protein S6 | 2223 | -0.320 | -0.4261 | Yes |
| 40 | RPS7 | RPS7 Entrez, Source | ribosomal protein S7 | 2225 | -0.326 | -0.4195 | Yes |
| 41 | RPS3A | RPS3A Entrez, Source | ribosomal protein S3A | 2245 | -0.343 | -0.4184 | Yes |
| 42 | MAGOH | MAGOH Entrez, Source | mago-nashi homolog, proliferation-associated (Drosophila) | 2273 | -0.366 | -0.4194 | Yes |
| 43 | RPL18 | RPL18 Entrez, Source | ribosomal protein L18 | 2291 | -0.376 | -0.4170 | Yes |
| 44 | RPL27 | RPL27 Entrez, Source | ribosomal protein L27 | 2315 | -0.403 | -0.4159 | Yes |
| 45 | RPS3 | RPS3 Entrez, Source | ribosomal protein S3 | 2324 | -0.410 | -0.4099 | Yes |
| 46 | RPS18 | RPS18 Entrez, Source | ribosomal protein S18 | 2327 | -0.414 | -0.4018 | Yes |
| 47 | RPS21 | RPS21 Entrez, Source | ribosomal protein S21 | 2331 | -0.416 | -0.3939 | Yes |
| 48 | RPL13A | RPL13A Entrez, Source | ribosomal protein L13a | 2350 | -0.432 | -0.3907 | Yes |
| 49 | RPS25 | RPS25 Entrez, Source | ribosomal protein S25 | 2379 | -0.451 | -0.3902 | Yes |
| 50 | RPL8 | RPL8 Entrez, Source | ribosomal protein L8 | 2406 | -0.477 | -0.3885 | Yes |
| 51 | RPS24 | RPS24 Entrez, Source | ribosomal protein S24 | 2468 | -0.526 | -0.3972 | Yes |
| 52 | RPL13 | RPL13 Entrez, Source | ribosomal protein L13 | 2477 | -0.536 | -0.3885 | Yes |
| 53 | UPF2 | UPF2 Entrez, Source | UPF2 regulator of nonsense transcripts homolog (yeast) | 2482 | -0.539 | -0.3784 | Yes |
| 54 | RPS26 | RPS26 Entrez, Source | ribosomal protein S26 | 2508 | -0.564 | -0.3745 | Yes |
| 55 | RPS15A | RPS15A Entrez, Source | ribosomal protein S15a | 2529 | -0.588 | -0.3686 | Yes |
| 56 | RPL18A | RPL18A Entrez, Source | ribosomal protein L18a | 2544 | -0.601 | -0.3604 | Yes |
| 57 | RPS12 | RPS12 Entrez, Source | ribosomal protein S12 | 2545 | -0.602 | -0.3477 | Yes |
| 58 | RPL24 | RPL24 Entrez, Source | ribosomal protein L24 | 2568 | -0.627 | -0.3416 | Yes |
| 59 | RPL17 | RPL17 Entrez, Source | ribosomal protein L17 | 2581 | -0.638 | -0.3320 | Yes |
| 60 | RPL5 | RPL5 Entrez, Source | ribosomal protein L5 | 2587 | -0.643 | -0.3200 | Yes |
| 61 | RPL14 | RPL14 Entrez, Source | ribosomal protein L14 | 2593 | -0.647 | -0.3080 | Yes |
| 62 | RPS4X | RPS4X Entrez, Source | ribosomal protein S4, X-linked | 2610 | -0.670 | -0.2990 | Yes |
| 63 | RPL23A | RPL23A Entrez, Source | ribosomal protein L23a | 2618 | -0.683 | -0.2868 | Yes |
| 64 | RPL37A | RPL37A Entrez, Source | ribosomal protein L37a | 2640 | -0.711 | -0.2786 | Yes |
| 65 | RPL7 | RPL7 Entrez, Source | ribosomal protein L7 | 2649 | -0.722 | -0.2659 | Yes |
| 66 | RPSA | RPSA Entrez, Source | ribosomal protein SA | 2659 | -0.732 | -0.2534 | Yes |
| 67 | RPL19 | RPL19 Entrez, Source | ribosomal protein L19 | 2665 | -0.735 | -0.2395 | Yes |
| 68 | RPL34 | RPL34 Entrez, Source | ribosomal protein L34 | 2667 | -0.739 | -0.2242 | Yes |
| 69 | RPL30 | RPL30 Entrez, Source | ribosomal protein L30 | 2669 | -0.742 | -0.2088 | Yes |
| 70 | RPL10 | RPL10 Entrez, Source | ribosomal protein L10 | 2701 | -0.776 | -0.2025 | Yes |
| 71 | RPL31 | RPL31 Entrez, Source | ribosomal protein L31 | 2718 | -0.794 | -0.1909 | Yes |
| 72 | RPLP2 | RPLP2 Entrez, Source | ribosomal protein, large, P2 | 2727 | -0.803 | -0.1765 | Yes |
| 73 | RPL35 | RPL35 Entrez, Source | ribosomal protein L35 | 2733 | -0.811 | -0.1610 | Yes |
| 74 | RPL3 | RPL3 Entrez, Source | ribosomal protein L3 | 2740 | -0.822 | -0.1456 | Yes |
| 75 | RPL36 | RPL36 Entrez, Source | ribosomal protein L36 | 2752 | -0.838 | -0.1314 | Yes |
| 76 | RPS10 | RPS10 Entrez, Source | ribosomal protein S10 | 2762 | -0.859 | -0.1162 | Yes |
| 77 | RPL35A | RPL35A Entrez, Source | ribosomal protein L35a | 2783 | -0.885 | -0.1040 | Yes |
| 78 | RPS11 | RPS11 Entrez, Source | ribosomal protein S11 | 2803 | -0.914 | -0.0908 | Yes |
| 79 | RPL38 | RPL38 Entrez, Source | ribosomal protein L38 | 2804 | -0.916 | -0.0715 | Yes |
| 80 | RPLP1 | RPLP1 Entrez, Source | ribosomal protein, large, P1 | 2806 | -0.919 | -0.0524 | Yes |
| 81 | RPL9 | RPL9 Entrez, Source | ribosomal protein L9 | 2848 | -0.979 | -0.0450 | Yes |
| 82 | UPF3B | UPF3B Entrez, Source | UPF3 regulator of nonsense transcripts homolog B (yeast) | 2880 | -1.032 | -0.0332 | Yes |
| 83 | RPS23 | RPS23 Entrez, Source | ribosomal protein S23 | 2894 | -1.046 | -0.0154 | Yes |
| 84 | RPL22 | RPL22 Entrez, Source | ribosomal protein L22 | 3020 | -1.357 | -0.0272 | Yes |
| 85 | RPS17 | RPS17 Entrez, Source | ribosomal protein S17 | 3048 | -1.454 | -0.0052 | Yes |
| 86 | RPL23 | RPL23 Entrez, Source | ribosomal protein L23 | 3149 | -2.132 | 0.0075 | Yes |
