Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | all-ab-ratio-log-sorted |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | REACTOME_MITOTIC_G1_G1_S_PHASES |
| Enrichment Score (ES) | 0.578908 |
| Normalized Enrichment Score (NES) | 2.1199355 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MCM4 | MCM4 Entrez, Source | MCM4 minichromosome maintenance deficient 4 (S. cerevisiae) | 89 | 1.993 | 0.0173 | Yes |
| 2 | CDK1 | 99 | 1.906 | 0.0584 | Yes | ||
| 3 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 121 | 1.768 | 0.0924 | Yes |
| 4 | PRIM2 | 128 | 1.741 | 0.1307 | Yes | ||
| 5 | MCM3 | MCM3 Entrez, Source | MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) | 165 | 1.556 | 0.1550 | Yes |
| 6 | TYMS | TYMS Entrez, Source | thymidylate synthetase | 172 | 1.542 | 0.1886 | Yes |
| 7 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 191 | 1.490 | 0.2172 | Yes |
| 8 | MCM2 | MCM2 Entrez, Source | MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae) | 204 | 1.449 | 0.2468 | Yes |
| 9 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 218 | 1.401 | 0.2749 | Yes |
| 10 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 222 | 1.392 | 0.3061 | Yes |
| 11 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 240 | 1.326 | 0.3312 | Yes |
| 12 | PSMD6 | PSMD6 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 277 | 1.243 | 0.3483 | Yes |
| 13 | PSMD8 | PSMD8 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 311 | 1.176 | 0.3648 | Yes |
| 14 | MCM5 | MCM5 Entrez, Source | MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 319 | 1.166 | 0.3895 | Yes |
| 15 | RPS27A | RPS27A Entrez, Source | ribosomal protein S27a | 323 | 1.157 | 0.4152 | Yes |
| 16 | UBA52 | UBA52 Entrez, Source | ubiquitin A-52 residue ribosomal protein fusion product 1 | 324 | 1.157 | 0.4419 | Yes |
| 17 | RRM2 | RRM2 Entrez, Source | ribonucleotide reductase M2 polypeptide | 346 | 1.129 | 0.4612 | Yes |
| 18 | PPP2CA | PPP2CA Entrez, Source | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | 372 | 1.081 | 0.4781 | Yes |
| 19 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 430 | 1.005 | 0.4830 | Yes |
| 20 | SKP1 | 484 | 0.935 | 0.4875 | Yes | ||
| 21 | PSMC3 | PSMC3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 499 | 0.910 | 0.5040 | Yes |
| 22 | PPP2R1A | PPP2R1A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform | 521 | 0.891 | 0.5178 | Yes |
| 23 | PSME1 | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 566 | 0.848 | 0.5232 | Yes |
| 24 | PSME2 | PSME2 Entrez, Source | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 570 | 0.840 | 0.5416 | Yes |
| 25 | PSMB9 | PSMB9 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 684 | 0.719 | 0.5218 | Yes |
| 26 | PSMD5 | PSMD5 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | 749 | 0.665 | 0.5165 | Yes |
| 27 | PSMC2 | PSMC2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 770 | 0.649 | 0.5251 | Yes |
| 28 | PSMB7 | PSMB7 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 7 | 797 | 0.622 | 0.5310 | Yes |
| 29 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 798 | 0.622 | 0.5454 | Yes |
| 30 | PSMD9 | PSMD9 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 | 852 | 0.577 | 0.5416 | Yes |
| 31 | PSMD14 | PSMD14 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 861 | 0.564 | 0.5521 | Yes |
| 32 | PSMB1 | PSMB1 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 1 | 871 | 0.557 | 0.5620 | Yes |
| 33 | CUL1 | CUL1 Entrez, Source | cullin 1 | 927 | 0.515 | 0.5562 | Yes |
| 34 | PSMA2 | PSMA2 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 2 | 940 | 0.504 | 0.5640 | Yes |
| 35 | PSMB10 | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 960 | 0.493 | 0.5692 | Yes |
| 36 | PSMC1 | PSMC1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 966 | 0.490 | 0.5789 | Yes |
| 37 | PSMB8 | PSMB8 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 1081 | 0.406 | 0.5516 | No |
| 38 | PSMC5 | PSMC5 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | 1124 | 0.371 | 0.5466 | No |
| 39 | PSMD3 | PSMD3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 1262 | 0.281 | 0.5090 | No |
| 40 | PSMC6 | PSMC6 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 1298 | 0.254 | 0.5036 | No |
| 41 | RPA1 | RPA1 Entrez, Source | replication protein A1, 70kDa | 1299 | 0.253 | 0.5094 | No |
| 42 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 1309 | 0.247 | 0.5122 | No |
| 43 | PSMB2 | PSMB2 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 2 | 1343 | 0.227 | 0.5068 | No |
| 44 | PSMD7 | PSMD7 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog) | 1362 | 0.215 | 0.5060 | No |
| 45 | PSMA4 | PSMA4 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 4 | 1441 | 0.159 | 0.4845 | No |
| 46 | RBBP4 | RBBP4 Entrez, Source | retinoblastoma binding protein 4 | 1469 | 0.145 | 0.4792 | No |
| 47 | PSMA1 | PSMA1 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 1 | 1476 | 0.140 | 0.4805 | No |
| 48 | PSMB3 | PSMB3 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 3 | 1481 | 0.134 | 0.4823 | No |
| 49 | PSMD12 | PSMD12 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 1490 | 0.128 | 0.4826 | No |
| 50 | PSMA3 | PSMA3 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 3 | 1562 | 0.081 | 0.4617 | No |
| 51 | PSMD11 | PSMD11 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 1585 | 0.069 | 0.4562 | No |
| 52 | PSMA6 | PSMA6 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 6 | 1600 | 0.057 | 0.4530 | No |
| 53 | PSMD13 | PSMD13 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 1641 | 0.041 | 0.4410 | No |
| 54 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 1659 | 0.029 | 0.4362 | No |
| 55 | PSMA7 | PSMA7 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 7 | 1675 | 0.020 | 0.4319 | No |
| 56 | PSMB4 | PSMB4 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 4 | 1713 | -0.002 | 0.4200 | No |
| 57 | POLA1 | POLA1 Entrez, Source | polymerase (DNA directed), alpha 1 | 1726 | -0.009 | 0.4163 | No |
| 58 | PSMC4 | PSMC4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 1732 | -0.011 | 0.4150 | No |
| 59 | PSMF1 | PSMF1 Entrez, Source | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 1755 | -0.023 | 0.4084 | No |
| 60 | PSMB6 | PSMB6 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 6 | 1868 | -0.099 | 0.3746 | No |
| 61 | PSMA5 | PSMA5 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 5 | 1900 | -0.115 | 0.3673 | No |
| 62 | PSMD1 | PSMD1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 1957 | -0.151 | 0.3528 | No |
| 63 | PSMD10 | PSMD10 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 2041 | -0.202 | 0.3307 | No |
| 64 | CDK7 | CDK7 Entrez, Source | cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) | 2214 | -0.314 | 0.2826 | No |
| 65 | PSMD4 | PSMD4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 2230 | -0.329 | 0.2853 | No |
| 66 | PSMB5 | PSMB5 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 5 | 2284 | -0.372 | 0.2768 | No |
| 67 | RPA3 | RPA3 Entrez, Source | replication protein A3, 14kDa | 2295 | -0.378 | 0.2824 | No |
