Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | all-ab-ratio-log-sorted |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | REACTOME_CHROMOSOME_MAINTENANCE |
| Enrichment Score (ES) | -0.52743816 |
| Normalized Enrichment Score (NES) | -1.9243225 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0027603304 |
| FWER p-Value | 0.06 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PRIM2 | 128 | 1.741 | 0.0115 | No | ||
| 2 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 240 | 1.326 | 0.0160 | No |
| 3 | HSPA2 | HSPA2 Entrez, Source | heat shock 70kDa protein 2 | 397 | 1.039 | -0.0025 | No |
| 4 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 430 | 1.005 | 0.0175 | No |
| 5 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 448 | 0.974 | 0.0414 | No |
| 6 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 511 | 0.903 | 0.0488 | No |
| 7 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 608 | 0.784 | 0.0417 | No |
| 8 | RFC4 | RFC4 Entrez, Source | replication factor C (activator 1) 4, 37kDa | 631 | 0.765 | 0.0577 | No |
| 9 | SMC3 | SMC3 Entrez, Source | structural maintenance of chromosomes 3 | 685 | 0.718 | 0.0624 | No |
| 10 | POLD2 | POLD2 Entrez, Source | polymerase (DNA directed), delta 2, regulatory subunit 50kDa | 742 | 0.670 | 0.0647 | No |
| 11 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 813 | 0.613 | 0.0608 | No |
| 12 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 1223 | 0.307 | -0.0604 | No |
| 13 | RPA1 | RPA1 Entrez, Source | replication protein A1, 70kDa | 1299 | 0.253 | -0.0767 | No |
| 14 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 1309 | 0.247 | -0.0721 | No |
| 15 | RBBP4 | RBBP4 Entrez, Source | retinoblastoma binding protein 4 | 1469 | 0.145 | -0.1185 | No |
| 16 | POLA1 | POLA1 Entrez, Source | polymerase (DNA directed), alpha 1 | 1726 | -0.009 | -0.1999 | No |
| 17 | RUVBL2 | RUVBL2 Entrez, Source | RuvB-like 2 (E. coli) | 2035 | -0.197 | -0.2921 | No |
| 18 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 2116 | -0.250 | -0.3101 | No |
| 19 | UBE2I | UBE2I Entrez, Source | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 2197 | -0.298 | -0.3267 | No |
| 20 | RPA3 | RPA3 Entrez, Source | replication protein A3, 14kDa | 2295 | -0.378 | -0.3462 | No |
| 21 | RUVBL1 | RUVBL1 Entrez, Source | RuvB-like 1 (E. coli) | 2318 | -0.405 | -0.3411 | No |
| 22 | LMNA | LMNA Entrez, Source | lamin A/C | 2571 | -0.632 | -0.4024 | No |
| 23 | HIST1H2AB | HIST1H2AB Entrez, Source | histone cluster 1, H2ab | 2964 | -1.185 | -0.4918 | Yes |
| 24 | HIST1H2AC | HIST1H2AC Entrez, Source | histone cluster 1, H2ac | 2965 | -1.185 | -0.4562 | Yes |
| 25 | HIST1H2AD | HIST1H2AD Entrez, Source | histone cluster 1, H2ad | 2966 | -1.185 | -0.4206 | Yes |
| 26 | HIST1H2AJ | HIST1H2AJ Entrez, Source | histone cluster 1, H2aj | 2969 | -1.185 | -0.3856 | Yes |
| 27 | HIST2H2AA3 | HIST2H2AA3 Entrez, Source | histone cluster 2, H2aa3 | 2970 | -1.185 | -0.3500 | Yes |
| 28 | HIST2H2AC | HIST2H2AC Entrez, Source | histone cluster 2, H2ac | 2971 | -1.185 | -0.3144 | Yes |
| 29 | HIST1H2BC | HIST1H2BC Entrez, Source | histone cluster 1, H2bc | 2995 | -1.263 | -0.2837 | Yes |
| 30 | HIST1H2BD | HIST1H2BD Entrez, Source | histone cluster 1, H2bd | 2996 | -1.263 | -0.2457 | Yes |
| 31 | HIST1H2BH | HIST1H2BH Entrez, Source | histone cluster 1, H2bh | 2997 | -1.263 | -0.2078 | Yes |
| 32 | HIST1H2BK | HIST1H2BK Entrez, Source | histone cluster 1, H2bk | 2998 | -1.263 | -0.1698 | Yes |
| 33 | HIST1H2BL | HIST1H2BL Entrez, Source | histone cluster 1, H2bl | 2999 | -1.263 | -0.1318 | Yes |
| 34 | HIST1H2BM | HIST1H2BM Entrez, Source | histone cluster 1, H2bm | 3000 | -1.263 | -0.0938 | Yes |
| 35 | HIST1H2BN | HIST1H2BN Entrez, Source | histone cluster 1, H2bn | 3001 | -1.263 | -0.0558 | Yes |
| 36 | SMC1A | SMC1A Entrez, Source | structural maintenance of chromosomes 1A | 3080 | -1.595 | -0.0328 | Yes |
| 37 | HIST1H4A | HIST1H4A Entrez, Source | histone cluster 1, H4a | 3143 | -2.055 | 0.0092 | Yes |
