Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | all-ab-ratio-log-sorted |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS |
| Enrichment Score (ES) | 0.51871634 |
| Normalized Enrichment Score (NES) | 1.7928231 |
| Nominal p-value | 0.0030816642 |
| FDR q-value | 0.01387966 |
| FWER p-Value | 0.195 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CDK1 | 99 | 1.906 | 0.0488 | Yes | ||
| 2 | UBE2E1 | UBE2E1 Entrez, Source | ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast) | 152 | 1.597 | 0.0996 | Yes |
| 3 | UBE2C | UBE2C Entrez, Source | ubiquitin-conjugating enzyme E2C | 219 | 1.398 | 0.1375 | Yes |
| 4 | PSMD6 | PSMD6 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 277 | 1.243 | 0.1718 | Yes |
| 5 | PSMD8 | PSMD8 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 311 | 1.176 | 0.2109 | Yes |
| 6 | RPS27A | RPS27A Entrez, Source | ribosomal protein S27a | 323 | 1.157 | 0.2563 | Yes |
| 7 | UBA52 | UBA52 Entrez, Source | ubiquitin A-52 residue ribosomal protein fusion product 1 | 324 | 1.157 | 0.3051 | Yes |
| 8 | PSMC3 | PSMC3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 499 | 0.910 | 0.2879 | Yes |
| 9 | PSME1 | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 566 | 0.848 | 0.3026 | Yes |
| 10 | PSME2 | PSME2 Entrez, Source | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 570 | 0.840 | 0.3371 | Yes |
| 11 | PSME4 | PSME4 Entrez, Source | proteasome (prosome, macropain) activator subunit 4 | 648 | 0.749 | 0.3441 | Yes |
| 12 | PSMB9 | PSMB9 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 684 | 0.719 | 0.3632 | Yes |
| 13 | PSMD5 | PSMD5 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | 749 | 0.665 | 0.3708 | Yes |
| 14 | PSMC2 | PSMC2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 770 | 0.649 | 0.3919 | Yes |
| 15 | PSMB7 | PSMB7 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 7 | 797 | 0.622 | 0.4098 | Yes |
| 16 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 798 | 0.622 | 0.4361 | Yes |
| 17 | PSMD9 | PSMD9 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 | 852 | 0.577 | 0.4435 | Yes |
| 18 | PSMD14 | PSMD14 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 861 | 0.564 | 0.4647 | Yes |
| 19 | PSMB1 | PSMB1 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 1 | 871 | 0.557 | 0.4854 | Yes |
| 20 | PSMA2 | PSMA2 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 2 | 940 | 0.504 | 0.4849 | Yes |
| 21 | PSMB10 | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 960 | 0.493 | 0.4996 | Yes |
| 22 | PSMC1 | PSMC1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 966 | 0.490 | 0.5187 | Yes |
| 23 | PSMB8 | PSMB8 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 1081 | 0.406 | 0.4994 | No |
| 24 | PSMC5 | PSMC5 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | 1124 | 0.371 | 0.5016 | No |
| 25 | PSMD3 | PSMD3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 1262 | 0.281 | 0.4696 | No |
| 26 | PSMC6 | PSMC6 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 1298 | 0.254 | 0.4691 | No |
| 27 | PSMB2 | PSMB2 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 2 | 1343 | 0.227 | 0.4646 | No |
| 28 | PSMD7 | PSMD7 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog) | 1362 | 0.215 | 0.4680 | No |
| 29 | PSMA4 | PSMA4 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 4 | 1441 | 0.159 | 0.4497 | No |
| 30 | PSMA1 | PSMA1 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 1 | 1476 | 0.140 | 0.4448 | No |
| 31 | PSMB3 | PSMB3 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 3 | 1481 | 0.134 | 0.4491 | No |
| 32 | PSMD12 | PSMD12 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 1490 | 0.128 | 0.4520 | No |
| 33 | PSMA3 | PSMA3 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 3 | 1562 | 0.081 | 0.4327 | No |
| 34 | PSMD11 | PSMD11 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 1585 | 0.069 | 0.4286 | No |
| 35 | PSMA6 | PSMA6 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 6 | 1600 | 0.057 | 0.4265 | No |
| 36 | PSMD13 | PSMD13 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 1641 | 0.041 | 0.4154 | No |
| 37 | PSMA7 | PSMA7 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 7 | 1675 | 0.020 | 0.4057 | No |
| 38 | PSMB4 | PSMB4 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 4 | 1713 | -0.002 | 0.3939 | No |
| 39 | PSMC4 | PSMC4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 1732 | -0.011 | 0.3886 | No |
| 40 | PSMF1 | PSMF1 Entrez, Source | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 1755 | -0.023 | 0.3826 | No |
| 41 | PSMB6 | PSMB6 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 6 | 1868 | -0.099 | 0.3509 | No |
| 42 | PSMA5 | PSMA5 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 5 | 1900 | -0.115 | 0.3459 | No |
| 43 | PSMD1 | PSMD1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 1957 | -0.151 | 0.3343 | No |
| 44 | PSMD10 | PSMD10 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 2041 | -0.202 | 0.3163 | No |
| 45 | PSMD4 | PSMD4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 2230 | -0.329 | 0.2701 | No |
| 46 | CDC16 | CDC16 Entrez, Source | CDC16 cell division cycle 16 homolog (S. cerevisiae) | 2254 | -0.354 | 0.2776 | No |
| 47 | PSMB5 | PSMB5 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 5 | 2284 | -0.372 | 0.2841 | No |
